PRP Injection

How is PRP injection used in Regenerative Medicine?

PRP Injection Facial Rejuvenation is now available at Advanced Liposuction Center!

Prp injection Pittsburgh

Platelet-Rich Plasma (PRP Injection Facial Rejuvenation), similar to a vampire facial, is a combination of microneedling and the application of Platelet-Rich Plasma. Used in sports medicine for years, this liquid gold contains multiple factors that stimulate the production of new blood vessels, elastic fibers and collagen. By stimulating collagen and elastin growth, PRP has been shown to kick the healing process into overdrive.

prp wexford

Tube of blood is placed in a medical centrifuge for plasma lifting

Your own blood is gently drawn by our phlebology specialist and centrifuged to extract the PRP. After a topical numbing cream has done its job to get one comfortable, the patient then undergoes a microneedling treatment. The applied PRP and microneedling combination allows for deeper penetration and optimal results to reduce fine lines and wrinkles, shrink pores, and leave your skin glowing, usually in less than a week.

What is Platelet Rich Plasma (PRP) and how is it made? 

The body is designed to heal itself. Ideally, a patient’s blood brings everything that’s needed for healing to occur exactly where it’s needed. The injured area is flooded with chemicals which call attention to the damaged tissue. The body mounts its normal regenerative response, and the tissue heals itself.

upmc prp

Face with open pores and melasma before and after treatment.

It doesn’t always heal completely or as well as possible, however. This is often the case in chronic ligament and tendon injuries. These tough, ropey structures have a naturally poor blood supply and can have difficulty healing on their own.

Platelet Rich Plasma is exactly what it sounds like. To prepare the PRP solution your doctor will use, they will first take a sample of your blood. Usually only 1 or 2 vials (vacutainers) are needed.

This whole blood is then processed using a centrifuge, a medical device which spins the vials at high speeds. In this way the contents of the blood are separated into distinct layers after only a few minutes. The doctor can then harvest the thin, shiny, platelet rich layer near the middle of the vial using a syringe. When these highly concentrated platelets are added to plain plasma the final PRP solution is ready for immediate use. It can contain upwards of 1,2000% the amount of platelets found in normal, unprocessed blood.

What, exactly, makes up the solution used in Platelet Rich Plasma (PRP) injections?

To date, there are no universally acknowledged guidelines stating what each milliliter of Platelet Rich Plasma fluid must contain. This is due in large part to the natural variations in each individual patient’s blood. Remember that PRP solution is a patient-sourced blood product, not a pharmaceutical preparation.

Research has instead shown that platelet-rich solutions containing between 3.5 and 9% platelets by volume to be the most consistently effective. While higher concentrations have been used there does not appear to be any appreciable additional benefit past this point. While not experimentally demonstrated, it is believed that PRP solutions containing extremely high concentrations of platelets will be less effective.

Remember that PRP isn’t a pharmaceutical drug such as cortisone, a commonly injected liquid steroid. This medication comes in pre-measured vials containing a precise amount of the active drug, and by law it must be clearly labeled as such. PRP solution is derived entirely from a patient’s own tissue so pharmaceutical laws aren’t relevant.

The role of white blood cells and the immune response in Platelet Rich Plasma therapy.

Platelets are only one of several cell or cell-like bodies found in our blood. White blood cells, or leukocytes, play a central part in the body’s immune response. They’re also active in other important (and related) processes such as inflammation and healing.

What doctors and laypersons alike call “healing” is actually an incredibly complicated undertaking we’re just beginning to fully understand. It is known that white cells contribute to full, complete, normal healing. Yet platelets, other cell types, and literally hundreds proteins and thousands of other chemicals are also involved.

Other considerations for success of PRP:

  • General health—individuals who take care of their physical health through diet, exercise, and proper healthcare will receive the best results. This is true of almost any medical intervention. Age is only one of several considerations.
  • Immunosuppression—patients with a compromised immune system may receive less of a benefit from PRP. Medications such as corticosteroids should be discontinued before starting PRP. They may be resumed afterwards if needed.
  • Nature of injury—for obvious reasons less injury is always better.

What is Platelet Rich Plasma (PRP) and how is it made? 

The body is designed to heal itself. Ideally, a patient’s blood brings everything that’s needed for healing to occur exactly where it’s needed. The injured area is flooded with chemicals which call attention to the damaged tissue. The body mounts its normal regenerative response, and the tissue heals itself.

It doesn’t always heal completely or as well as possible, however. This is often the case in chronic ligament and tendon injuries. These tough, ropey structures have a naturally poor blood supply and can have difficulty healing on their own.

Platelet Rich Plasma is exactly what it sounds like. To prepare the PRP solution your doctor will use, they will first take a sample of your blood. Usually only 1 or 2 vials (vacutainers) are needed.

This whole blood is then processed using a centrifuge, a medical device which spins the vials at high speeds. In this way the contents of the blood are separated into distinct layers after only a few minutes. The doctor can then harvest the thin, shiny, platelet rich layer near the middle of the vial using a syringe. When these highly concentrated platelets are added to plain plasma the final PRP solution is ready for immediate use. It can contain upwards of 1,2000% the amount of platelets found in normal, unprocessed blood.

vampire facial

woman wrinkles before and after procedures

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